Dynamic Oxygen-Enhanced MRI of Cerebrospinal Fluid
نویسندگان
چکیده
منابع مشابه
Dynamic Oxygen-Enhanced MRI of Cerebrospinal Fluid
Oxygen causes an increase in the longitudinal relaxation rate of tissues through its T1-shortening effect owing to its paramagnetic properties. Due to such effects, MRI has been used to study oxygen-related signal intensity changes in various body parts including cerebrospinal fluid (CSF) space. Oxygen enhancement of CSF has been mainly studied using MRI sequences with relatively longer time re...
متن کاملMeasurement of arterial plasma oxygenation in dynamic oxygen-enhanced MRI.
Inhaled oxygen can be used as a contrast agent for magnetic resonance imaging, due to the T(1) shortening effect of the oxygen dissolved in blood and tissue water. In this study, blood T(1) was measured dynamically in 14 volunteers (seven smokers, seven never-smokers) as the inhaled gas was switched from medical air to 100% oxygen and back to medical air. These T(1) values were converted to cha...
متن کاملDynamic oxygen-enhanced MRI in patients with pulmonary arterial hypertension
Introduction: Oxygen-enhanced MRI (O2-MRI) of the lung is based on the T1-shortening effect of oxygen (O2) inhalation and provides combined information about pulmonary ventilation, perfusion, and diffusion [1–9]. Dynamic O2-MRI acquires (in each pixel) the signal time course influenced by the alternating administration of room air and O2. By fitting a model function (pixelwise) to the acquired ...
متن کاملDynamic oxygen-enhanced lung MRI: Cross-correlation analysis and oxygen-activated pixels
Introduction: In oxygen-enhanced MRI (O2-MRI) of the lung, the inhalation of pure oxygen (O2) decreases the longitudinal relaxation time, T1, of blood, which can be detected by T1-weighted MRI [1–9]. Frequently, a block paradigm is used for O2-MRI consisting of a series of T1-weighted scans acquired during alternating blocks with inhalation of room air and O2. This block design results in a sig...
متن کاملOxygen-enhanced MRI of the Lung
Highlights • Molecular oxygen is paramagnetic and lowers the T1 of nearby protons • Altering the concentration of inhaled O2 changes lung T1-weighted signal • Potential tool for assessing lung function with widespread availability • While usually considered a measure of regional lung ventilation, likely also a function of regional perfusion • Emerging methods address inherently low SNR and impr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLoS ONE
سال: 2014
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0100723